The Department of Translational & Regenerative Medicine, under the headship of Prof. Reena Das, organized a one day seminar cum workshop (14.05.26) in collaboration with MTPL on the characterization of extracellular vesicles (EVs) from biological fluids and stem cell secretome. The event was aimed to introduce faculty and students to the growing importance of EVs in modern biomedical research. The programme began with expert talks by Dr. Aruna Rakha from the Department of Translational & Regenerative Medicine and Dr. Priyanka Srivastava from the Advanced Paediatric Centre, who explained the biological role of EVs and their emerging clinical relevance in a manner accessible to researchers, clinicians and students.
Extracellular vesicles are tiny particles released by cells that carry important biological information, such as proteins and genetic material. Since EVs can be found in easily accessible body fluids such as blood, urine and other biological samples, their study may help in developing less invasive methods for disease detection and monitoring. In the future, EV-based tests may support early diagnosis, help doctors understand disease progression and allow better tracking of treatment response without the need for repeated invasive procedures. EVs are being explored as biomarkers in several metabolic, neuronal, cardiac and immune-mediated diseases, and have also entered as therapeutic intervention in clinical trials for conditions such as acute respiratory distress syndrome, dry eye disease and wound healing.
A key highlight of the workshop was the hands-on training session on Nanoparticle Tracking Analysis (NTA) using the ZetaView TWIN platform. Mr. Chaitanya from MTPL explained the working principles and applications of NTA, demonstrating how this powerful technique can measure and characterize EVs based on their size, concentration and fluorescence tagged identifying antibodies. The practical session provided faculty and students valuable exposure to advanced technology used in EV research and helped bridge the gap between laboratory-based discoveries and their possible clinical applications for patient benefit.
